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Saiki Kusuo no Psi-nan (斉木楠雄のΨ難 Saiki Kusuo no Sainan, lit. "The Disaster of Psi Kusuo Saiki") is a Japanese gag manga series written and illustrated by Shūichi Asō. Individual chapters have been serialized in Weekly Shōnen Jump since May 2012 until February 2018. An additional 2 chapters were released in May and July of 2018 in Shōnen Jump GIGA. All the chapters were collected into tankōbon volumes and published by Shueisha. As of 2018, there are 26 volumes that have been published. The manga inspired an anime series that premiered in July 4, 2016. Funimation streamed the anime under the title "The Disastrous Life of Saiki K." with English subtitles as it aired in Japan, and produced an English dub for the series' first season. A second anime season premiered in mid-January 2018 and a special that premiered in late December 2018. The series has a live-action film that opened in Japan on October 21, 2017. Recently, The Disastrous Life of Saiki K.: Reawakened, a Netflix Original Anime Series, was released on December 30, 2019.

Born with innate supernatural power, Kusuo Saiki seems to have his life easy. He possess various psychic abilities, including telepathy and psychokinesis among others, allowing him to get anything he wants. During kindergarten, he unintentionally caught the attention of the local media after rumors of his Rock paper scissors matches against his classmates and teacher spread around town. Since the incident, Kusuo has been particularly careful with using his powers in public, but coming into his sophomore year of high school, with all hi-jinks that ensued, Kusuo began to relax on this habit.