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Saiki Kusuo no Psi-nan (斉木楠雄のΨ難 Saiki Kusuo no Sainan, lit. "The Disaster of Psi Kusuo Saiki") is a Japanese gag manga series written and illustrated by Shūichi Asō. Individual chapters have been serialized in Weekly Shōnen Jump since May 2012 until February 2018. An additional 2 chapters were released in May and July of 2018 in Shōnen Jump GIGA. All the chapters were collected into tankōbon volumes published by Shueisha. As of 2018, there are 26 volumes released. The manga inspired an anime series that premiered in July 4, 2016. Funimation streamed the anime under the title "The Disastrous Life of Saiki K." with English subtitles as it aired in Japan, and produced an English dub for the series' first season. A second anime season premiered in mid-January 2018 and a special that premiered in late December 2018. The series has a live-action film that opened in Japan on October 21, 2017. Recently, Netflix announced that it will produce an original anime series that will release in late December 2019.

Born with innate supernatural powers, Saiki Kusuo seems to have his life easy. He possesses various psychic abilities, including telepathy and psychokinesis among others, allowing him to get anything he wants. During kindergarten, he incidentally caught media attention after rumors of how he never loses any janken match against his friends and teacher spread around town. The incident made him came to the resolve of not using his power in front of others ever again so people will not find out that he is a psychic. But upon being a high school sophomore, with all hi-jinks that ensue, Kusuo is slowly cutting his resolve loose.